Gender-Affirming care (GAC) is a multidisciplinary field of medicine designed to treat gender dysphoria—the clinical distress caused by a mismatch between a person’s gender identity and their sex assigned at birth. It is not a single treatment; rather, it’s a customizable, step-wise framework designed to meet each individual’s needs, goals, and developmental stage.
Collaborative: Involves physicians, mental health providerss, endocrinologists, and social workers.
Evidence-based: Major medical associations (e.g., AMA, AAP, Endocrine Society, WPATH) recognize gender-affirming care as medically necessary for many transgender people.
Developmentally appropriate: Interventions differ between children, adolescents, and adults.
Focused on well-being: The primary goal is reducing distress (gender dysphoria) and improving quality of life, functioning, and mental health.
The benefits are generally categorized into psychological, social, and physiological outcomes.
Here is the current clinical consensus as of 2026.
Reduced Suicidality: Major studies (including 2025/2026 longitudinal cohorts) consistently show that access to hormone therapy is associated with a dramatic decrease in suicidal ideation and attempts. In some cohorts, 60% of those with baseline suicidal ideation reported none after one year of treatment. https://www.mdpi.com/3396826
Lower Rates of Depression & Anxiety: Patients often report a “lifting of a fog.” Clinical scores for depression (PHQ-9) and anxiety (GAD-7) typically show meaningful reductions within 6 to 12 months of beginning care.
Body Image Congruence: GAC helps patients achieve “physical alignment,” which reduces the severe distress associated with secondary sex characteristics (like facial hair or chest shape) that do not match their identity. https://pmc.ncbi.nlm.nih.gov/articles/PMC12604846/
While often focused on “transitioning,” GAC also includes preventative and maintenance care.
Hormonal Balance: For those who have undergone certain surgeries, hormone therapy is medically necessary to maintain bone density and prevent osteoporosis.
Improved Sexual Health: Many patients report higher levels of sexual satisfaction and a reduction in “sexual avoidance” once their bodies feel more congruent with their identity.
Second Puberty: Hormone therapy triggers physical changes—such as fat redistribution, skin softening, or voice deepening—that allow individuals to move through the world more safely and authentically.